Haemophilus Influenzae B

Immunogenicity and Efficacy of Different Haemophilus influenzae type b Vaccines

Haemophilus influenzae, a major cause of meningitis in young children leading to death and other neurological sequelae. The disease leaves 15 to 35% of the survivors with permanent disabilities, such as, mental retardation or deafness. Despite the availability of new and more powerful antibiotics children with Hib meningitis still suffer from high mortality or morbidity. The emergence of multir...

Haemophilus influenzae Type b Meningitis

The age-related acquisition of serum anticapsular and bactericidal antibodies to Haemophilus influenzae type b observed in rats was similar to that of humans. The antigenic source for this "natural" immunity was not identified, since neither pharyngeal infection with H. influenzae b nor enteric colonization by cross-reacting bacteria was detected. Infant rats surviving H. influenzae b bacteremi...

Haemophilus influenzae type b pneumonia.

Thirteen patients with Haemophilus influenzae type b pneumonia are reported to emphasise the clinical, radiographic, and therapeutic aspects of this illness. All but one patient was under 2 1/2 years of age. The presenting complaint was a variable duration of upper respiratory infection and fever in most cases. One-third of patients had radiographic evidence of pleural involvement; one-third sh...

Haemophilus Influenzae Type B Disease

Before the introduction of effective vaccines, H. influenzae, type b (Hib) was the leading cause of bacterial meningitis and other invasive bacterial disease among children less than 5 years of age. In 1997, ten confirmed cases of invasive disease caused by the serotype b strain of H. influenzae were reported. This is the first year that the number of cases increased since the conjugate vaccine...

Haemophilus influenzae type B septicaemia.

In the period November 1967 to September 1968 Haemophilus influenzae type b was isolated from the blood of 11 young children. Only three of these presented with meningitis; others had septic arthritis, oesteomyelitis, subcutaneous abscesses, cellulitis, respiratory infections, and undifferentiated pyrexia. During the preceding five years H. influenzae type b was isolated from the blood cultures...

Haemophilus influenzae type b conjugate vaccine.